DEPARTMENT OF LIFE SCIENCE
Life Science
Infrastructure
State of Research laboratory facilities are available and equipped with sophisticated instruments
Generic Name of Equipment | Model, Make & year of purchase |
---|---|
CO2 Incubator | Model 3111, (ThermoFisher Scientific, USA), 2013 |
Phase Contrast Inverted Microscope | Axio Vert A1 FL (Carl Zeiss, Germany), 2013 |
Western Blot Semi Dry | TE70X (Hoefer, USA), 2013 |
Gel Electrophoresis Horizontal | SE250-10A-75 mighty small II mini vertical electrophoresis (Hoefer, USA), 2013 |
Gel Electrophoresis Vertical | SUB15 standard submarine gel system (Hoefer, USA), 2013 |
Gel Documentation Unit | GelDoc –IT imaging system (UVP LTD, UK), 2013 |
Phase Contrast Inverted Fluorescence Microscope | Axio Vert A1 FL (Carl Zeiss, Germany), 2013 |
Western Blot Semi Dry | Trans blot turbo (Biorad, USA), 2013 |
Western Blot wet | Standard transfer unit with cooling chamber (Hoefer, USA), 2013 |
Chemiluminiscent Gel Documentation Unit | ChemiDoc MP system with red module (Biorad,USA), 2013 |
Freeze Dryer | Alpha 2-4 Ldplus (Martin Christ, Germany), 2013 |
Real Time PCR | CFX96 (Biorad, USA), 2013 |
CO2 Incubator | Galaxy incubator 170R (Eppendorf, USA), 2013 |
Deep Freezer -80C | Premium upright freezer U410 (Eppendorf, USA), 2013 |
Deep Freezer -20C | Revco -20 (ThermoFisher Scientific, USA), 2013 |
High performance liquid chromatography (HPLC) With PDA & Fluorescence Detector | LC-2010CHT (Shimadzu, Japan), 2013 |
Gel Electrophoresis Horizontal | Mini Sub GT Cell (Biorad, USA), 2013 |
Gel Electrophoresis Vertical | Mini-PROTEAN Tetra (Biorad, USA), 2013 |
Manual Colony Counter | Scan 100 (Intersciences, France), 2013 |
Multiporator | Multiporator, for eukaryotics, bacteria and yeasts (Eppendorf,USA), 2013 |
Spectrophotometer | BioSpectrometer basic (Eppendorf, USA), 2013 |
Multimode Reader With Alpha Tech | Enspire multilabel plate reader with Alpha Tech (PerkinElmer, USA), 2013 |
PCR | Mastercycler nexus gradient (Eppendorf, USA), 2013 |
Infrastructure and Labs
The school has sufficient number of well equipped class rooms, fully equipped laboratories with state of the art equipments, conference hall, school and library. The school has the following laboratories adequately equipped with latest equipments
- Molecular biology lab
- Biochemistry lab
- Genetics lab
- Microbiology lab
- Computational biology lab
- Plant tissue culture lab
- Animal tissue culture lab
- Central research laboratory
Equipments
Chemi-luminescent Gel-documentation Unit, BioRad, USA
- Gel imaging system, Automated, hands-off routines
- Save and recall all the steps in the workflow for repeatable and reproducible results.
- Comprehensive, automated quantitative analysis of protein and DNA samples
Phase Contrast Inverted Fluorescence Microscope, Carl Zeiss, Germany
- The phase contrast microscope was developed visualize specimens that fluoresce, that is, emit light of a different color than the light absorbed by the specimen.
- This microscope has stable time-lapse imaging with automatic focus correction system.
Lyophilizer, Martin Christ
- Lyophilized (freeze dried) products retain their original properties.
- There is no need for cooling during storage
- There is a wide range of substances for which lyophilization is used as conservation / preservation method
- In the pharmaceutical and biotechnology industries it is widely used for the following products: antibiotics, bacteria, vaccines, hormones, vitamins, enzymes, ferments, peptides, liposomes, collagen, plant extracts, blood plasma and antibodies.
Mastercycler nexus gradient, Eppendorf India Limited
- Master cycler (PCR) is an exponentially progressing synthesis of the defined target DNA sequences under in vitro.
- PCR used for classification of organisms, genotyping, molecular archaeology, mutagenesis, mutation detection, sequencing, cancer research, detection of pathogens, DNA fingerprinting, drug discovery, genetic matching and engineering.
Multiporator, Eppendorf India Limited
- Utilzeed for the electroporation of eukaryotic cells, bacteria and other microorganisms, as well as the electrofusion of cells possible with Eppendorf Multiporator modular system. The applications includes
- Makes stable and transient transfection of eukaryotic cells
- Efficient and gentle transfer of siRNA
- Electroporation of bacteria, yeasts and other microorganisms
- Generation of hybridoma cells for the production of monoclonal antibodies
- Fusion of plant protoplasts
Real-time PCR , Eppendorf India Limited
- Real-time PCR is used for sensitive, specific detection and quantification of nucleic acid targets.
- This system has powerful assay design algorithms, optimized master mixes, intuitive data analysis software and flexible instrumentation to harness the power of qPCR across a rich and diverse set of applications. The applications include
- Gene Expression (mRNA) analysis
- microRNA & Noncoding RNA analysis
- Genetic variation analysis
- Mutation detection Assays
Probe Sonicator
- Sonication is the act of applying sound energy to agitate particles in a sample, for various purposes. Ultrasonic frequencies (>20 kHz) are usually used, leading to the process known asr ultra-sonication.
- Sonicators are used for a wide variety of applications including: Protein purification, Degassing, PMCA, Sono-chemistry, Liposomes, Crystallization, Emulsification, Extraction, Transesterification, focused Cleaning, and solubilize the compounds
Binary Gradient HPLC system, Shimadzu
- This instrument is used to separate the components in a mixture to identify each component, and to quantify each component.
- It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material.
- Each component in the sample interacts slightly differently with the adsorbent material, causing different flow rates for the different components and leading to the effective separation of the components as they flow out of the column.
Thermostat C, Eppendorf India Limited
- The ideal device to accurately set and maintain temperatures. The ThermoStat C features excellent temperature management.
- Provides comfortable and precise temperature control of all conventional lab vessels.
- The operation is easier and more intuitive than ever before.
- Predefined temperature keys provide quick access to five important experimental temperatures.
- Due to comprehensive program functions, one can also individually store 15 programs. With an extensive range of exchangeable Smart Blocks, the ThermoStat C adapts to any application.
Gel Doc, Labmate (Asia) PVT LTD
- A gel doc, also known as a gel documentation system, gel image system or gel imager, is an equipment widely used in molecular biology laboratory for the imaging and documentation of nucleic acid and protein suspended within polyacrylamide or agarose gels.
- Generally, a gel doc includes an ultraviolet (UV) light transilluminator, or darkroom to shield external light sources and protect the user from UV exposure, and a
- CCD camera for image capturing
Table-top Centrifuge, Eppendorf
- A mini spin (centrifuge) is a piece of equipment, generally driven by an electric motor
- The centrifuge works using the sedimentation principle, where the centripetal acceleration causes denser substances to separate out along the radial direction.
- Simple centrifuges are used in chemistry, biology and biochemistry for isolating and separating suspensions.
Gel Electrophoresis Vertical and Horizontal, BioRad
- Gel electrophoresis is a method for separation and analysis of macromolecules (DNA, RNA and proteins) and their fragments, based on their size and charge.
- Estimation of the size of DNA molecules following restriction enzyme digestion, e.g. in restriction mapping of cloned DNA.
- Analysis of PCR products, e.g. in molecular genetic diagnosis or genetic fingerprinting
- Separation of restricted genomic DNA prior to Southern transfer, or of RNA prior to Northern transfer.
- Gel electrophoresis is used in forensics, molecular biology, genetics, microbiology and biochemistry.
Multimode Reader with Alpha Tech, PerkinElmer
- The benchtop multimode instrument to feature label-free technology
- Ultra-sensitive luminescence option for detecting fewer cells than standard luminescence, ideal for primary, stem or difficult-to-transfect cells
- Quad-monochromator for fluorescence and absorbance – select any wavelength and perform wavelength scans for the best possible signal to background for fluorescence applications
- Time-resolved fluorescence provides high sensitivity for biological and cellular assays, even when sample is at a premium or in low concentration.
Western Blot Semi Dry, Biorad
- Western electroblotting is the electrophoretic transfer of separated proteins in a gel to the surface of a thin support membrane matrix where they are bound and immobilized.
- Semi-dry blotting is performed with plate electrodes in a horizontal configuration, sandwiching a gel and membrane between sheets of buffer-soaked filter paper that function as the ion reservoir.
- Western transfer amino acid analysis solid phase assay systems
- Protein sequencing Western transfer, amino acid analysis solid phase assay systems.
- Southern and northern transfers solid phase immobilization dry chemistry test strips, enzyme immobilization, gene probe assays
Phase Contrast Inverted Microscope, Micros Produktions
- Phase contrast microscopy is an optical microscopy technique that converts phase shifts in light passing through a transparent specimen to brightness changes in the image.
- The phase contrast microscope shows the contrast differences between cells.
- This microscope has stable time-lapse imaging with automatic focus correction system
- Improved performance in broader wavelength range Compatible with plastic dishes and well plates
Upright Freezer, Eppendorf and Deep Freezer, Thermo Fisher Scientific
- Deep freezer, a stand-alone freezer unit for preserving research samples
- This deep freezer generally can achieve lower than −80 °C
- Upright freezer from Eppendorf India Limited and other deep Freezer from Thermo Fisher Scientific are available in the school.
Autoclave, Technico
- An autoclave is a pressure chamber used to sterilize equipment and media by subjecting them to high pressure saturated steam at 121 °C for around 15–20 minutes depending on the size of the load and the contents.
- Sterilization autoclaves are widely used in microbiology, medicine, podiatry, tattooing, body piercing, veterinary science, mycology, dentistry, and prosthetics fabrication. They vary in size and function depending on the media to be sterilized.
Centrifuge 5810R, Eppendorf India Limited
- A centrifuge is a piece of equipment, generally driven by an electric motor and this centrifuge has refrigeration option to use temperature sensitive sample.The centrifuge works using the sedimentation principle, where the centripetal acceleration causes denser substances to separate out along the radial direction. By the same token lighter objects will tend to move to the top.
- Simple centrifuges are used in chemistry, biology and biochemistry for isolating and separating suspensions.
SLS Journal club
SLS Journal club
The main purpose of SLS Journal club is the critical review of the key papers in Life Science research. Each meeting will be held with the participation of scholars, students and faculty members to discuss and critique research that appears in professional journals of related field. Understanding and forming a precise opinion of a journal article is a crucial skill for research; the SLS Journal Club aims to equip the research scholars and students with the skills necessary to carry out a critical review of literature relevant to their field and also to keep everyone updated about the global scenario in multidisciplinary research. Further information and weekly updates about the club can be found in following weblink: https://journalclubsls.wordpress.com/
Internships Offered
International Internship Offered
Industrial attachment program for students from Universiti Teknologi Mara (UiTM) Samarahan Campus, Sarawak, Malaysia
Four students from Universiti Teknologi Mara (UiTM) Samarahan Campus,, Sarawak, Malaysia has done research internship at school of life sciences between 1st August to 4th September 2015 on phytocompounds and their applications to cure infections and cancer.
Name of the student | Name of the guide | Title of the project |
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Mohammad Hairaze Ezwandy Bin Adenan | Dr.S.Hemalatha | Antimicrobial activity and isolation of active compounds from leaf of the traditional african medicinal tree Kigelia africana (LAM) benth |
Mozzarie Shahrayzam Bin Masidi | Dr.S.Hemalatha | Extraction and characterization of phytochemical compounds from Hemidesmus indicus L. |
Gerald Grino Apil | Dr.S.Hemalatha | Detection of heavy metals in soil sediments |
Dominic Anak Geruka | Dr.S.Hemalatha | Antibacterial and anticancerous efficacy of flavonoids isolated, purified and characterized from various parts of couroupita guianensis. |
National summer internship offered in Science for school student
From May 4-22, 2015 B.S.Abdur Rahman Institute organized free SummerInternship in Science programme for School Students. Out of 30 selected students from various schools , 11 students were done their projects at SLS and the ist, 2nd and third prizes are bagged by Ms. Santhoshini, Mr. Mothi and Ms. Divya lakshmi respectively and the projects are listed in the table below.
Sno | Name of the student | NAME OF THE SCHOOL | NAME OF THE SUPERVISOR | TITLE OF THE PROJECT |
---|---|---|---|---|
1 | Mohamed Sheik Mothi | Alpha Mat.Hr.Sec.School, Sembakkam | Testing the efficacy of anti diabetic drug to control the pathogenic bacteria causing diabetic foot ulcer. | Novel method of delivering drugs to control UTI pathogens and testing their efficacy |
2 | Divya Lakshmi.K | Sri Vishwa Vidyalaya Hr.Sec.School,Vandalr | Dr.S.Hemalatha | Novel method of delivering drugs to control UTI pathogens and testing their efficacy |
3 | Athira.P.S | Neelan Mat. School, Guduvancheri. | Dr. Karthikeyan. R | Antibiotic susceptibility assay of commercially available three different antibiotic tablets on human pathogen |
4 | Sakthi Priya.M | Neelan Mat. School, Guduvancheri. | Antibiotic susceptibility assay of commercially available antibiotic on human pathogen | |
5 | Sabeena.B | Ebenezer Mat.School, New Perungalathur. | Dr. Khurshid Alam Khan | Ebola Virus: Unravelling pathogenesis & Treatment Strategies |
6 | Jeevitha.M | Ebenezer Mat.School, New Perungalathur. | Dr. Soumen Bera | Quantification of polyphenols in common food sources. |
7 | Pon Dharanieswari.P | Anitha Methodist Hr.Sec. School ,Vepery. | Dr. Neesar Ahmed | Characterization of Blood and Its component. |
8 | Thejal.H | Ebenezer Mat.School, New Perungalathur. | Dr. Shazia Jamal | Quantification of Proteins |
9 | Raeesah Firdhouse.S | Crescent Girls Mat.Hr.Sec School, Nungambakkam | Er.Kavitha | Green Bags to preserve and delay ripening of fruits |
10 | Santhoshini.J | Ebenezer Mat.School, New Perungalathur. | Dr. M.K.Sangeetha | Impact of an environmental influencing factor on Chick Embryogenesis |
11 | Hounandan.R | St.Anne’s Mat.Hr.Sec.School,New Perungalathur | Dr. Amrita Roy | Diabetic Food–eat or delete? |
Faculty Achievements
Faculty Achievements
Name of the Faculty | Achievements |
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Dr. S. Hemalatha |
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Dr. R. Karthikeyan |
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Dr. P. Ashok Kumar |
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Dr. Khurshid A. Khan |
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Dr. Soumen Bera |
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Dr. Neesar Ahmed |
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Dr. Shazia Jamal |
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Dr. Shahul Hameed |
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Dr. Sudarkodi Sukumar |
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Dr. Shahanabaj Khan |
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Dr. G. Harish |
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Scholars Achievements
Name of the Research Scholar | Achievements |
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Saroj Kumar Sah |
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S.M. Fazeela Mahaboob Begum |
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Mohamed Adil |
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K. Rekha Yamini |
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Ubaid Rasool |
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Tahira Akthar |
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Sneha. U |
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Logesh .R, |
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Students Achievements
Name of the Student | Achievements |
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Ms. Hemashri. R. M and Ms. B. Chandini |
participated in Guinness world records event Bharatha Natyam, on 14, April, 2017 |
KIRUTHIGA. A. P. | Chennai International youth Festival and won |
Vinodhini .S | won “Best Revolutionary project award” in ‘Sarvashastra 2017’ organized by MGR University |
Sugirdhana .P | won Best Science & Technology project award in ‘Sarvashastra 2017’ organized by MGR University |
Mohammed Faheem | PECOFES 2017-spell Bee won |
Ms. Zakia Fathima | DBT sponsored Biotech Industrial Training Programme (BITP) with BCIL fellowship. |
B. Famidha | won second prize in poster presentation in National conference on applications of Green Technologies for separations of Bio-products, Sree Sastha Institute of Engg. & Technology September 2-3, 2015 |
4.1 International Internhips
4.1.1. Mohamed Adil I year B.Tech Biotechnology student from School of Life Sciences has done one month summer internship at Department of Pathology Johns Hopkins School of Medicine, USA from June 1-30, 2015.
4.1.22. Four students from II year B.Tech have been selected from school of life sciences for summer internship at Department of Pathology, Johns Hopkins School of Medicine, USA for 2 months.
4.1.3. Abeer, I year B.Tech from School of Life Sciences has done one month summer internship at King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia.
4.2 National Internships
4 .2.2. B. Amrutha I year B.Tech Biotechnology student from School of Life Sciences has done one month summer internship at Central Leather Research Institute, Chennai
4.2.3. Xinovem private limited Chennai selected 32 B.Tech students for winter internship 2015 and individual project is assigned for the students for the winter 2015.
4.2.4 Divij K Kinger has been selected as intern for Entrepreneurship Training with scholarship in Pentagrit research, Chennai